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Resolving rather than reducing inflammation

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Table of Contents

  1. Acute versus chronic inflammation
  2. Trauma
  3. Loneliness
  4. Resolving versus reducing inflammation
  5. When reducing inflammation does not work
  6. Summary

Inflammation is a defence mechanism initiated by the body’s immune system in response to perceived harmful stimuli such as trauma, infection, and/or auto-immune disease.1 The purpose of inflammation is to initiate healing, making it crucial to both recovery and repair.

Key highlights

  • Inflammation is a defense mechanism by the immune system in response to harmful stimuli, essential for healing and repair.
  • Acute inflammation occurs rapidly and resolves with the help of cytokines and leukocytes. Unresolved acute inflammation can become chronic, lasting for months or years.
  • The transition from inflammation to resolution involves the synthesis of SPMs from omega-3 fatty acids.
  • Individuals with chronic conditions often have impaired pathways for producing SPMs, which are crucial for resolving inflammation.
Figure 1. Acute versus chronic inflammation33

Topics

Irritabale Bowel SyndromeExercise recoveryDiabetic neuropathyDental reliefCarpal tunnelChronic painAnti inflammatoryAnti histamineIBSOverweightObesityStressPalmitoylethanolamideOsteoarthritisMigraineJoint PainInflammationDysmenorrheaDepressionAnxietyAnhedonia